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Kim, Yon Hui Sarah

Yon Hui Sarah Kim Ph.D., MBA(full-time professor)
Faculty Appointment
(title, department)
Associate Professor, Department of System Cancer Science, GCSP
Adjunct Professor, Univ. of Texas MD Anderson Cancer Center
Area of Expertise
Biochemical and Bioengineering
Contact no
Previous Appointment(s) Held
Chief, Office of Technology Transfer, NCC (2013-present)
Chief Branch, New Experimental Therapeutics, Division of Convergence and Technology, NCC (2012-present)
Asst. Professor, Experimental Therapeutics Dept. Division of Cancer Medicine, MDACC (2008-2011)
Educational Background
B.S. Eastern Michigan University, Medical Microbiology, USA. (1989)
M.S. University of Michigan, Biotechnology and Chemical Engineering, College of Engineering, USA. (1991)
Ph.D. The University of Tokyo, Biochemistry and Biotechnology, College of Engineering, Japan. (2001)
MBA Rice University, Jones Graduate School of Business, USA, (2010)
Research Interests(Please place in paragraph form)
Dr. YH Kim current research specialties are in early and late preclinical research and development of personalized targeted therapy. Focuses are in development of biomarkers, and druggable targets for treatment of gastric cancer.
International Collaboration
UT MD Anderson Cancer Center, Experimental Therapeutics Dept.
Sanford-Burnham Medical Research Institute, Cancer Center
2016 SCI-E Improving gastric cancer preclinical studies using diverse in vitro and in vivo model systems: BMC Cancer. 16(1):200~200 (3.265)

2015 SCI Ad5/35E1aPSESE4: a Novel Approach to Marking Circulating Prostate Tumor Cells with a Replication Competent Adenovirus Controlled by PSA/PSMA Transcription Regulatory Elements: Cancer Letters. 382(1):57~64 (5.621)

2015 SCI-E Network Comparison of Inflammation in Colorectal Cancer and Alzheimer’s Disease: BioMed Research International. 2015:205247~205247 (1.579)

2015 SCI A pathway-based approach for identifying biomarkers of tumor progression to trastuzumab-resistant breast cancer: Cancer letters. 356(2 Pt B):880~890 (5.621)

2014 SCI HNF4α is a therapeutic target that links AMPK to WNT signalling in early-stage gastric cancer: Gut. 65(1):19~32 (13.319)

2014 SCI-E Mg2+ effect on argonaute and RNA duplex by molecular dynamics and bioinformatics implications.: PloS one. 9(10):e109745~e109745 (3.534)

2014 SCI PATHOME: an algorithm for accurately detecting differentially expressed subpathways: Oncogene. 33(41):4941~4951 (8.559)

2014 SCI The condensin component NCAPG2 regulates microtubule-kinetochore attachment through recruitment of Polo-like kinase 1 to kinetochores.: Nature Communications. 5:4588~4588 (10.742)

2014 SCI A nanowire-based label-free immunosensor: Direct incorporation of a PSA antibody in electropolymerized polypyrrole: Biosensors & bioelectronics. 57:157~161 (6.451)

2014 SCI Detection of PIWI and piRNAs in the mitochondria of mammalian cancer cells: Biochemical and Biophysical Research Communications. 446(1):218~223 (2.281)

2014 SCI An Electroactive Biotin-Doped Polypyrrole Substrate That Immobilizes and Releases EpCAM-Positive Cancer Cells: Angewandte Chemie (International ed. in English). 53(18):4597~4602 (11.336)

2013 SCI Identifying molecular drivers of gastric cancer through next-generation sequencing: Cancer Letters. 340:241~246 (4.258)

2012 SCI AMPKα modulation in cancer progression: multilayer integrative analysis of the whole transcriptome in Asian gastric cancer: Cancer Research. 75(10):2512~2521 (7.856)

2011 SCI Antitumor agent PX-12 inhibits HIF-1α protein levels through an Nrf2/PMF-1-mediated increase in spermidine/spermine acetyl transferase: Cancer Chemotherapy and Pharmacology. 68:405~413 (2.833)

2010 SCI The Homeobox Gene Hex Regulates Hepatocyte Differentiation from Embryonic Stem Cell?Derived Endoderm: Hepatology. 51:633~641 (11.665)

2000 SCI-E Establishment of an apoptosis-suppressible,cell-cycle arrestable cell line and its applicationfor enhancing protein production of serum-free or-supplemented culture: Cytotechnology. 32:125~134 (1.315)

2000 SCI Inhibition of c-Jun expression induces antioxidant enzymes under serum deprivation: Archives of Biochemistry and Biophysics. 374:339~346 (3.097)

2000 SCI Apoptosis induced by hydrogen peroxide under serum deprivation and its inhibition by antisense c-jun in F-MEL cells: Biochemical and Biophysical Research Communications. 271:747~752 (2.5)